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E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says

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Study Offers Hint of Hope for Staving Off Dementia in Some People

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When the Cat Needs a Painkiller

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Does Cannabis Use Cause Schizophrenia?

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Memorial Sloan Kettering Curbs Executives’ Ties to Industry After Conflict-of-Interest Scandals

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Sacklers Directed Efforts to Mislead Public About OxyContin, New Documents Indicate

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F.D.A. Says It Will Resume Inspecting Some High-Risk Foods

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Does Forskolin Actually Work? An Evidence-Based Review from Dr. Oz

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IRELAND READERS / RESIDENTS

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Losing weight can be extremely difficult.

First See, What Dr. Oz. Have to say about Forskolin

Studies show that only 15% of people succeed using 

conventional weight loss methods.

Those who fail are more likely to seek solutions like 

dietary supplements and herbal medicines.

One of them is called forskolin, a natural plant 

compound claimed to be an impressive weight 

loss supplement.

This article takes a detailed look at forskolin and 

the science behind it.

What is Forskolin?

Forskolin is an active compound found in the roots 

of the Indian coleus (Coleus forskohlii), a tropical 

plant related to mint.

For centuries, this plant has been used in traditional 

herbal medicine to treat various conditions and diseases.

Modern scientific research has now shown that some of 

these health benefits may be true, or at least plausible.

As a weight-loss supplement, forskolin gained popularity 

in the US after being featured on the Dr. Oz Show in January 2014.

BOTTOM LINE:Forskolin is an active compound found in the roots of the Indian coleus. It is sold as a weight-loss supplement.
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How Does Forskolin 

Help With Weight Loss?

Many studies have investigated the effects of forskolin on 

fat metabolism.

Most of them are test-tube experiments or animal studies, 

so the result may not be applicable to humans.

Put simply, forskolin stimulates the release of stored fat 

from fat cells. The same thing happens whenever the body 

needs to use body fat for energy.

On its own, the release of stored fat is not enough to 

promote weight loss - it needs to be accompanied by a calorie deficit.

In other words, for weight loss to happen, energy 

expenditure (calories out) must exceed energy intake (calories in).

Weight loss supplements can support a calorie deficit by:

• Suppressing appetite.
• Reducing efficiency of digestion.
• Increasing metabolic rate (fat burning).

As far as we know, forskolin does not cause any of these things to happen.

However, clinical trials in humans have provided some promising results. It appears that forskolin may promote fat loss while preserving muscle mass.

These effects are discussed in the next chapter.

Does Forskolin Actually

Help You Lose Weight?

So far, only two small studies have investigated the effects of 

forskolin on weight loss in humans.

Both of them were randomized controlled trials, the gold standard 

of scientific research in humans.

The largest trial recruited 30 overweight and obese men, who were 

then randomly assigned to two groups:

• Forskolin group: 15 men were supplemented with 250 mg of Coleus forskohlii extract (10% forskolin) twice a day for 12 weeks.
• Placebo group: 15 men took the same amount of dummy pills (placebo).

Compared to the placebo group, men who took forskolin lost significantly more fat, but total body weight did not change.

This is how body composition changed during the course of the study:

Additionally, there was a significant increase in free testosterone in the forskolin group. Testosterone can stimulate the release of fat from fat cells, which may partly explain the fat loss observed in the study.

A rise in testosterone can also promote an increase in muscle mass. In fact, there was a trend towards an increase in lean body mass in the forskolin group, but it was not statistically significant.

In the other study, 23 overweight women received the same dose of Coleus forskohlii (500 mg/day) for 12 weeks.

In contrast to the previous study, forskolin supplementation did not have any significant effects on fat loss, but the results suggested that forskolin may protect against weight gain.

In conclusion, 12-week supplementation with forskolin does not cause weight loss, but it may improve body composition in men and prevent weight gain in women.

All that being said, the current evidence is not strong enough to make any recommendations. More research is needed.

BOTTOM LINE:Two studies have investigated the effect of forskolin on weight loss. In one of them, supplementation caused significant fat loss, but body weight remained constant.
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Other Health Benefits of Forskolin Supplements

The Indian coleus plant (which contains Forskolin) has been a part of traditional herbal medicine for centuries.

It has been used to treat conditions such as heart disease, asthma, bronchitis and constipation.

In humans, forskolin supplements may also:

• Widen the air passages in the lungs, helping to relieve asthma.
• Increase bone mineral density, lowering the risk of osteoporosis.
• Stimulate testosterone formation, promoting the maintenance of muscle mass.

There are also studies in test tubes or laboratory animals indicating other benefits.

BOTTOM LINE:Forskolin has been a part of traditional herbal medicine for ages. Limited evidence suggests that it may help alleviate asthma, increase bone density and stimulate testosterone formation.
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Dosage and Side Effects

The typical dosage of forskolin is 100-250 mg of Coleus forskohlii (10% forskolin), twice per day.

Forskolin does not appear to have any adverse effects in humans, but its safety profile has not been fully evaluated.

Should You Try Forskolin?

Based on the current evidence, it is clear that forskolin does not cause weight loss.

However, one study in men indicates that it may raise testosterone levels and improve body composition, as in making you lose fat while increasing muscle mass.

At this point, the evidence is way too limited to reach any meaningful conclusions.

As a general rule, it is a good idea to be skeptical of all weight loss supplements. Some of them show promise in early studies, only to be proven completely ineffective in larger, higher quality studies.

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California Adds Its Clout to States Battling High Drug Prices

By KATIE THOMAS from NYT Health https://nyti.ms/2TICc48

The Flu Is Widespread in the U.S., and It’s Not Too Late to Get Vaccinated

By DENISE GRADY from NYT Health https://nyti.ms/2TP6lPl

Facing Legal Action, Insurer Now Will Cover People Taking Truvada, an H.I.V.-Prevention Drug

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What are probiotics?

Probitoics are often referred to as the good bacteria that line your gut 

and keep your digestive system healthy. Not only do probiotics help 

with restoring a healthy digestive system, but also they help to prevent 

the adverse effects of bad bacteria such as infections, rashes, irritations, 

and bacterial fungi. Gut health is essential for anyone who is looking to 

get the most out of their nutrition and diet.

What does this have to do with working out you say?

It may be the case that you are taking several other supplements in your 

workout regime, and perhaps you already combine this with a good, 

well balanced diet, but did you know that without having a healthy gut, 

you are wasting valuable nutrients that you could be absorbing. Take for 

instance a high protein diet. You know that lean meat, and protein powder 

costs add up considerably, so why would you want to waste your hard work 

in the gym and money at the supermarket just to nutrients into a leaky gut. 

It’s the same as putting gas in a car that has a leaky gas tank. By restoring 

you gut health with probiotic bacteria, you can absorb nutrients faster and 

more efficiently, allowing you to get the most out of what you put in.

How do you use probiotics?

Probiotics, being live bacteria are active in fermented foods such as yogurt, 

kimchi, kombucha, and pickles. They can be cultured also, and are commonly 

used in a supplement capsule form.

What dosage should you take?

If you are going to try finding a probiotic supplement, there are a few things 

you should want to take note of. One point is the potency and you’re going to 

want to find one that delivers a minimum potency of 30 billion probiotic bacteria 

per serving. Another point is the where the supplement has been manufactured. 

You want to make sure that the probiotic supplement was made with GMP 

standards and that it was stored in a temperature-controlled environment to 

protect the potency.

Where can you find probiotic supplements?

If you want to try probiotics out for yourself there are some great products out 

there that can get you started. See the link below for great deals on high quality 

probiotic supplements.